The 2018 Japan Leukemia Research Fund Awarding Ceremony was held on October 27, 2018 at the Incorporated Foundation, The Industry Club of Japan. The awards were given to 25 researchers and 1 group (JCCG HLH/LCH) this year.

Ogimura Takashi Special Prize

Keisuke Kataoka

[Division of Molecular Oncology, National Cancer Center Research Institute]

Elucidation of the role of immune-related genomic abnormalities in the tumor microenvironment

Shimizu Award

Yasuo Kubota

[Department of Pediatrics, The University of Tokyo Hospital]

Integrated genetic/epigenetic analysis of acute lymphoblastic leukemia in Down syndrome

Credit Saison Award

Yoko Tabe

[Juntendo University School of Medicine]

Identification of biomarkers of anti-leukemia efficacy of the novel oxidative phosphorylation(OxPhos) inhibitor focusing on the OxPhos dependence and immune suppression system of acute myeloid leukemia(AML) in the bone marrow microenvironment

Mainichi Award

Shunsuke Nakagawa

[Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences]

A novel treatment strategy for pediatric leukemia using a new mechanism to control p53

Special AwardClinical Medicine Special Award

Yuki Yuza

[Department of Hematology /Oncology, Tokyo Metropolitan Children’s Medical Center]

Phase 2 Clinical Trial for newly diagnosed pediatric, adolescent and young adult acute promyelocytic leukemia aiming to reduce the use of chemotherapeutic agents: AML-P17

Manabu Fujisawa

[Department of Hematology, Graduate School of Comprehensive Human Science, University of Tsukuba]

Activation of RHOA-VAVI signaling in angioimmunoblastic T-cell lymphoma

Kohta Miyawaki

[Department of Pathology, Kurume University]

Development of tumor microenvironment-based prognostic model and novel therapeutic strategy for diffuse large B-cell lymphoma

General Research AwardIn no particular order

Akihiko Yokoyama

[Tsuruoka Metabolomics Laboratory, National Cancer Center]

Development of novel therapy targeting transcriptional regulation by leukemic oncoproteins

Kensuke Kojima

[Division of Hematology, Respiratory Medicine and Oncology Department of Internal Medicine , saga University]

Overcoming resistance to Bruton’s tyrosine kinase inhibition in mantle cell lymphoma

Masao Nakagawa

[Department of Hematology, Hokkaido University Faculty of Medicine]

Utilization of CRISPR-Cas9 system for clarifying molecular mechanisms of sensitivity and resistance against drugs for refractory T-cell lymphomas

Tetsuya Mori

[Department of Pediatrics, St. Marianna University School of Medicine]

Clinical trial for untreated children with high risk mature B-cell non-Hodgkin lymphoma

Yoshiko Hashii

[Department of Pediatrics, Osaka Graduate School of Medicine]

Comprehensive analysis of pediatric leukemia by multifactor clustering involving immune regulation and epigenome

Haruka Wada

[Division of Immunology, Institute for Genetic Medicine, Hokkaido University]

Establishment of novel strategy that enables to control GVHD by selective immunosuppression

Maiko Matsushita

[Division of Clinical Physiology and Therapeutics, Keio University , Faculty of Pharmacy]

Detection of immunomodulatory drug for combined immunotherapy against multiple myeloma

Tomomi Toubai

[Department of Internal Medicine III, Yamagata University Faculty of Medicine]

Graft-versus-host disease(GVHD)- related acute kidney injury after allogeneic hematopoietic cell transplantation

Hideaki Makishima

[Department of Pathology and Tumor Biology, Kyoto University]

Integrated analysis of clonal dynamics in myelodysplastic syndromes

Akira Sakai

[Department of Radiation Life Sciences, Fukushima Medical University School of Medicine]

Elucidation of the mechanism of development of multiple myeloma using normal B lymphocyte derived iPS cells

Junya Kuroda

[Kyoto Prefectural University of Medicine]

Development of hit/lead compound targeting PDPK1/RSK2 signaling for multiple myeloma by means of cell – based assay

Research award for young researchersSpecial Award

Kentaro Hosokawa

[Department of Stem Cell Biology and Medicine, Kyushu University]

Functional analysis of telomere binding factors for energy metabolism of leukemia stem cells

Research award for young researchersIn no particular order

Ai Yamada

[Division of Pediatrics Faculty of Medicine, University of Miyazaki]

Comprehensive mutational analysis of genes related to complement activation in transplant – associated thrombotic microangiopathy

Hidemasa Matsuo

[Department of Human Health Sciences, Graduate School of Medicine, Kyoto University]

Investigation of D-type Cyclin genes’ 3’UTR abnormalities in pediatric acute myeloid leukemia

Yoshihiro Hayashi

[Laboratory of Oncology, Tokyo University of Pharmacy and life Sciences]

Targeting erythroblastic island macrophages in the pathogenesis of anemia in myeloid malignancies

Mariko Morii

[Runx Biology, International Research Center for Medical Science, Kumamoto University]

A molecularly targeted therapy against age-dependent t(8;21) leukemogenesis

Yuuki Obata

[Division of Cancer Differentiation, National Cancer Center Research Institute]

Mislocalization of mutant receptor tyrosine kinase in acute myeloid leukemia ~Oncogenic signaling on intracellular compartments~

Masayasu Hayashi

[Center for Cellular and Molecular Medicine, Kyushu University Hospital]

Development of novel therapy for leukemia targeting ZSCAN4, the novel molecule which maintains undifferentiated state of stem cells

2018 The Legend Special Award for the Group

JCCG(Japan Children’s Cancer Group) HLH/LC

Yozo Nakagawa

[Department of Pediatrics, Shinshu University School of Medicine]

Developing a new clinical trial for EB virus – associated hemophagocytic lymphohistiocytosis in children, adolescents and young adults

Award Recipient List of 2017-13